SE-ATLAS

Mapping of Health Care Providers
for People with Rare Diseases

ImmunDefektCentrum Leipzig (IDCL) am Klinikum St. Georg

Description of facility

Director / Spokesperson
Prof. Dr. med. Michael Borte
Information
Care facility for adults and children
Description
Das ImmunDefektCentrum Leipzig (IDCL) am Städtischen Klinikum St. Georg ist eines der deutschlandweit größten Therapie- und Diagnostikzentren für angeborene Störungen der Immunabwehr (Primäre Immundefekte). Im Einzugsbereich Sachsen, Thüringen, Sachsen-Anhalt und Nord-Bayern ist das IDCL Ansprechpartner für Immundefektpatienten sowohl im ambulanten als auch im stationären Bereich und ermöglicht eine nahtlose Diagnose und Behandlung der als „Seltene Erkrankungen“ eingestuften Abwehrstörungen.

Das interdisziplinäre Team aus Kinderärzten, Internisten, speziell ausgebildeten Krankenschwestern und klinischen Forschern hat sich zum Ziel gesetzt, die Versorgung von Immundefektpatienten zu verbessern, angeborene Immundefekte früher zu erkennen und klinisch-angewandte Forschung zu betreiben. In enger Zusammenarbeit mit dem Institut für Klinische Immunologie der Universität Leipzig, dem Fraunhofer Institut für Zelltherapie und Immunologie (IZI) Leipzig, sowie internationalen Kooperationspartnern, ist so beispielsweise der deutschlandweit erste Screeningtest für schwere Immundefekte entwickelt worden, der bereits bei Neugeborenen eingesetzt werden kann. Das IDCL koordiniert weiterhin internationale Therapiestudien zur Ersatztherapie mit körpereigenen Abwehrstoffen (Immunglobulinen).

Care provisions

This facility offers the following
  • Participation in registries
    Register der European Society for Immunodeficiencies (ESID) Register von FIND-ID.
  • Genetic counselling
  • Clinical studies / research
    Interleukin 21-basierte Immuntherapie von Patienten mit selektivem IgA-Mangel Arzneimittelzulassungsstudien Allergierisiko-Studien.
  • Diagnostic
  • Therapy
  • Contact person for patients with an unclear diagnosis
    Ungeklärte Infektionshäufungen, aussergewöhnliche und unerwartete Infektionserreger, unklare Fieberepisoden, rezidivierende Haut- und Organinfektionen.
  • Contact with support groups
    Deutsche Selbsthilfe Angeborene Immundefekte e.V. (DSAI)

Contact

Sekretariat
0341 9093660
0341 9093669
Website https://immunodeficiencycenterleipzig.jimdo.com/

Address

Delitzscher Straße 141
04129 Leipzig

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Languages

Germany.png Deutsch
United_Kingdom.png Englisch

Preview of the assigned diseases 1

Hemophagocytic syndrome X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia Poikiloderma with neutropenia Recurrent infections associated with rare immunoglobulin isotypes deficiency Tumor necrosis factor receptor 1 associated periodic syndrome Idiopathic CD4 lymphocytopenia Cernunnos-XLF deficiency Adult-onset immunodeficiency with anti-interferon-gamma autoantibodies Congenital neutropenia-myelofibrosis-nephromegaly syndrome Combined immunodeficiency due to ZAP70 deficiency Hermansky-Pudlak syndrome due to AP-3 deficiency Twin to twin transfusion syndrome Immunodeficiency predominantly affecting antibody production Cyclic neutropenia Susceptibility to respiratory infections associated with CD8alpha chain mutation Combined immunodeficiency due to CD3gamma deficiency Immunodeficiency syndrome with autoimmunity Immunodeficiency syndrome with hypopigmentation Pancytopenia due to IKZF1 mutations Adult idiopathic neutropenia T-cell immunodeficiency with epidermodysplasia verruciformis Combined immunodeficiency due to CD27 deficiency Severe combined immunodeficiency due to CORO1A deficiency Secondary hemophagocytic lymphohistiocytosis Immune dysregulation disease with immunodeficiency Griscelli syndrome type 2 Neutropenia-monocytopenia-deafness syndrome Primary hemophagocytic lymphohistiocytosis Lymphoproliferative syndrome Ataxia-telangiectasia Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome Functional neutrophil defect Majeed syndrome Constitutional neutropenia RAS-associated autoimmune leukoproliferative disease Nijmegen breakage syndrome Properdin deficiency Severe dermatitis-multiple allergies-metabolic wasting syndrome Primary immunodeficiency with natural-killer cell deficiency and adrenal insufficiency Monocytopenia with susceptibility to infections Combined immunodeficiency due to CRAC channel dysfunction Leukocyte adhesion deficiency Autosomal agammaglobulinemia Primary immunodeficiency due to a defect in innate immunity Autosomal recessive mendelian susceptibility to mycobacterial diseases due to a partial deficiency Chronic granulomatous disease NLRP3-associated autoinflammatory disease Chronic mucocutaneous candidiasis Severe combined immunodeficiency due to FOXN1 deficiency Combined immunodeficiency due to partial RAG1 deficiency Syndromic multisystem autoimmune disease due to Itch deficiency Hemophagocytic syndrome associated with an infection Immunodeficiency due to a complement cascade protein anomaly Barth syndrome Autosomal recessive mendelian susceptibility to mycobacterial diseases due to a complete deficiency LIG4 syndrome PAPA syndrome Primary immunodeficiency Immunodeficiency due to CD25 deficiency Combined immunodeficiency due to IL21R deficiency Good syndrome Mendelian susceptibility to mycobacterial diseases due to complete IFNgammaR2 deficiency X-linked immunoneurologic disorder Short-limb skeletal dysplasia with severe combined immunodeficiency Complement component 3 deficiency Acquired hemophagocytic lymphohistiocytosis associated with malignant disease Ataxia-telangiectasia-like disorder Autosomal dominant mendelian susceptibility to mycobacterial diseases due to a partial deficiency Immunoglobulin heavy chain deficiency Graft versus host disease Combined immunodeficiency due to DOCK8 deficiency Macrophage activation syndrome X-linked lymphoproliferative disease Autoimmune lymphoproliferative syndrome Osteopetrosis-hypogammaglobulinemia syndrome Bloom syndrome Mendelian susceptibility to mycobacterial diseases due to complete IL12B deficiency Neutrophil immunodeficiency syndrome Familial cold urticaria Severe combined immunodeficiency due to LCK deficiency T-cell large granular lymphocyte leukemia Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency Bacterial susceptibility due to TLR signaling pathway deficiency Shwachman-Diamond syndrome Genetic susceptibility to infections due to particular pathogens Vici syndrome Familial hemophagocytic lymphohistiocytosis Say-Barber-Miller syndrome Autosomal dominant hyper-IgE syndrome due to STAT3 deficiency Myeloperoxidase deficiency Papillon-Lefèvre syndrome T-cell immunodeficiency with thymic aplasia Dyskeratosis congenita Severe combined immunodeficiency due to DCLRE1C deficiency Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency T-B+ severe combined immunodeficiency due to gamma chain deficiency Primary immunodeficiency syndrome due to LAMTOR2 deficiency Leukocyte adhesion deficiency type II Severe combined immunodeficiency due to adenosine deaminase deficiency Autosomal recessive mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR2 deficiency Leukocyte adhesion deficiency type I Leukocyte adhesion deficiency type III Facial dysmorphism-immunodeficiency-livedo-short stature syndrome Susceptibility to viral and mycobacterial infections due to STAT1 deficiency Agammaglobulinemia-microcephaly-craniosynostosis-severe dermatitis syndrome Autosomal recessive mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR1 deficiency Combined immunodeficiency with granulomatosis Felty syndrome Autoimmune lymphoproliferative syndrome with recurrent viral infections Anti-HLA hyperimmunization Transient hypogammaglobulinemia of infancy Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR1 deficiency Familial isolated congenital asplenia Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency Hepatic veno-occlusive disease-immunodeficiency syndrome Dianzani autoimmune lymphoproliferative disease Pearson syndrome Hyperzincemia and hypercalprotectinemia Recurrent infection due to specific granule deficiency Activated PI3K-delta syndrome X-linked hyper-IgM syndrome Herpes simplex virus encephalitis PLCG2-associated antibody deficiency and immune dysregulation 22q11.2 deletion syndrome Constitutional neutropenia with extra-hematopoietic manifestations Hyper-IgM syndrome type 3 Combined immunodeficiency due to CARD11 deficiency Immunodeficiency due to a classical component pathway complement deficiency Hyper-IgM syndrome type 2 Hyper-IgM syndrome type 5 T-B+ severe combined immunodeficiency due to JAK3 deficiency Hyper-IgM syndrome type 4 Immunodeficiency by defective expression of MHC class II Immunodeficiency due to a late component of complement deficiency Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial IFNgammaR2 deficiency T-B+ severe combined immunodeficiency T-B+ severe combined immunodeficiency due to CD45 deficiency Muckle-Wells syndrome Epidermodysplasia verruciformis Other immunodeficiency syndromes due to defects in innate immunity Chédiak-Higashi syndrome Combined immunodeficiency due to STK4 deficiency Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency Nijmegen breakage syndrome-like disorder T-B- severe combined immunodeficiency Syndromic agammaglobulinemia Omenn syndrome Immunodeficiency due to MASP-2 deficiency Mendelian susceptibility to mycobacterial diseases due to partial STAT1 deficiency Isolated agammaglobulinemia Acquired immunodeficiency T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta Immunodeficiency due to ficolin3 deficiency Cartilage-hair hypoplasia Severe combined immunodeficiency due to DNA-PKcs deficiency Combined immunodeficiency due to ORAI1 deficiency Autoimmune enteropathy and endocrinopathy-susceptibility to chronic infections syndrome Roifman syndrome X-linked severe congenital neutropenia Autoimmune polyendocrinopathy type 1 Specific antibody deficiency with normal immunoglobulin concentrations and normal numbers of B cells X-linked mendelian susceptibility to mycobacterial diseases Kostmann syndrome X-linked agammaglobulinemia Severe congenital neutropenia Combined immunodeficiency with facio-oculo-skeletal anomalies Blau syndrome Hoyeraal-Hreidarsson syndrome Autoinflammatory syndrome with immune deficiency Combined immunodeficiency due to STIM1 deficiency X-linked mendelian susceptibility to mycobacterial diseases due to IKBKG deficiency Acquired neutropenia Severe combined immunodeficiency due to complete RAG1/2 deficiency Syndrome with combined immunodeficiency Laron syndrome with immunodeficiency Cohen syndrome Schimke immuno-osseous dysplasia Immunodeficiency due to absence of thymus Immunodeficiency with factor H anomaly Mendelian susceptibility to mycobacterial diseases due to complete IFNgammaR1 deficiency Primary immunodeficiency due to a defect in adaptive immunity Deficiency in anterior pituitary function-variable immunodeficiency syndrome X-linked mendelian susceptibility to mycobacterial diseases due to CYBB deficiency Immunodeficiency with factor I anomaly Susceptibility to infection due to TYK2 deficiency Hereditary neutrophilia Mendelian susceptibility to mycobacterial diseases Hypohidrotic ectodermal dysplasia with immunodeficiency Familial Mediterranean fever Hyper-IgE syndrome Hyperimmunoglobulinemia D with periodic fever Recurrent Neisseria infections due to factor D deficiency Lichtenstein syndrome Common variable immunodeficiency Selective IgM deficiency Sterile multifocal osteomyelitis with periostitis and pustulosis Rare immune disease Reticular dysgenesis FADD-related immunodeficiency Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome Autosomal dominant severe congenital neutropenia Purine nucleoside phosphorylase deficiency Immunodeficiency with isotype or light chain deficiencies with normal number of B-cells Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency Severe combined immunodeficiency Immunodeficiency due to selective anti-polysaccharide antibody deficiency Acute graft versus host disease Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome WHIM syndrome Other immunodeficiency syndrome with predominantly antibody defects Hyper-IgM syndrome without susceptibility to opportunistic infections Spondyloenchondrodysplasia Hyper-IgM syndrome with susceptibility to opportunistic infections Chronic graft versus host disease Immunodeficiency by defective expression of MHC class I Agammaglobulinemia ICF syndrome Immuno-osseous dysplasia Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia Absent thumb-short stature-immunodeficiency syndrome DNA repair defect other than combined T-cell and B-cell immunodeficiencies Combined T and B cell immunodeficiency Immunodeficiency with severe reduction in serum IgG and IgA with normal/elevated IgM and normal number of B-cells CINCA syndrome PFAPA syndrome Wiskott-Aldrich syndrome

Provided care options 1

# Contact person
1
Jeffrey Modell Zentrum für Immundefekt Leipzig
Prof. Dr. med. Michael Borte

0341 9093601
Email
Website
Sprechzeiten nach Vereinbarung.
This consultation offers genetic counselling.

12.37635612487793151.384149228931875ImmunDefektCentrum Leipzig (IDCL) am Klinikum St. Georg
Last updated: 09.11.2023